The article
Jorge, Elise, Hocking Toby D., Neuvial, Pierre, Vialaneix, Nathalie and Foissac, Sylvain (2026). hicream: a flexible framework to identify significantly different regions in Hi-C data.
has been accepted for publication in Bioinformatics. In this article, we describe a novel approach to account for spatial information in Hi-C differential analysis. The method has been implemented in the R package hicream, available on CRAN, and is part of Elise Jorge’s PhD work.